Generally speaking, our skin begins to lose age when we hit 50. This is brought about by changes in epidermal pH, the permeability barrier, and hydration levels. The permeability barrier helps the skin retain water and repel harmful pathogens and bacteria. 

Low-level inflammation or Inflammaging is triggered by the increase of molecules called cytokines in the blood. Breaks in the permeability barrier lead to a loss of moisture causing the skin to release these harmful cytokines. In younger people these cytokines are able to repair the permeability barrier, however, as we age, the barrier becomes increasingly difficult to fix, allowing these cytokines to reach the blood. Once an increased number of these cytokines reach the bloodstream, it triggers a domino effect of multiple health problems.

An effective skincare plan involves the use of three types of lipids – free fatty acids, ceramides, and cholesterol. These are critically important for general skin health and overall wellbeing and health. 

Chronic vs Acute Inflammation

Chronic Skin Inflammation

Chronic skin inflammation includes problems such as rosacea, eczema, psoriasis, etc. These are brought about by a number of reasons including poor diet and a sustained exposure to irritants. 

Though it is less noticeable on the surface, chronic skin inflammation manifests itself by fever, fatigue, and a general feeling of illness. Chronic inflammation and elevated cytokine levels may lead to permanent skin damage. 

The medical community is exploring whether a lowering of cytokine levels can prevent or delay age-related inflammatory problems.

Acute Skin Inflammation

Acute skin inflammation is a rapid onset of skin problems brought about by acne, sunburn, allergies, infections, bug bites, or reactions to certain creams or irritants. It is mostly manifested through pain, swelling, fatigue, fever, and redness. 

Unlike chronic skin inflammation, acute skin inflammation does not usually lead to permanent skin damage and is usually short-lived. In most cases, it is resolved in a day or week. 

Adding CBD to Your Skincare Regimen

The three layers of skin in the human body – epidermis, dermis, and hypodermis – contain a number of different cells that work in conjunction with each other are a part of an inter-related neural-network governed by the human body’s endocannabinoid system or ECS. 

The ECS is responsible for a homeostatic process known as cutaneous cannabinoid signaling that plays a part in repairing skin cells, promoting healthy skin, and better functioning of the permeable barrier.

An in vitro study by Italian scientists published in Phytotherapy Research in 2019 concluded that CBD isolate compounds in CBD oils regulated a number of genes that were involved in the healing of wounds and countering skin inflammation. CBD is a great source of Vitamins A, D, and E, as well as essential fatty acids – omega 3 and 6. It is also well known for its antioxidant properties. All of these are excellent reasons why CBD works well when it comes to improving the health and general youthfulness of our skin.

With the help of the PPAR receptor (Peroxisome proliferator-activated receptor), CBD displays antioxidant and anti-inflammatory properties that are either comparable to or stronger than vitamins like A and E. 

Additionally, the Beta caryophyllene and Phytol contained in CBD are terpenes with calming and anti-inflammatories that help in repairing skin and healing surface wounds. Beta Caryophyllene is also helpful when it comes to regulating stress response genes.

Disclaimer

CBD products that are derived from Hemp and contain less than the prescribed .3 percent of THC are legal per federal law. However, certain state laws may still deem it illegal.

CBD products that are derived from Marijuana are illegal per federal law but remain legal under the laws of certain states. 

It is advisable to check the appropriate state laws in case of travel. It is important to note that over-the-counter CBD products are not approved by the FDA.